The mission of the BNI-ASU Center for Preclinical Imaging is to provide state-of-the-art imaging technology and expertise for researchers in the Phoenix area. Key to that goal is our 7-Tesla Bruker Biospec MRI scanner. The center is a joint effort between Barrow Neurological Institute and Arizona State University with the goal of providing a key piece of core technology and advancing science across the Valley.
Over the last decade, high-field MRI systems have opened the door to new discoveries in biology and medicine. Investigators can use this cutting-edge resource to examine, in vivo, both the anatomy and function in their preclinical models. In addition to advanced technology, the center also provides imaging expertise to help researchers develop and implement their imaging protocols.
ACTIVE PROJECTS
| Investigator | Institution | Study |
|---|---|---|
| Kevin Bennett | ASU | MRI techniques to detect single renal glomerular function in nephritic mice |
| Kevin Bennett | ASU | Implantable MRI reporter gels with picolmolar sensitivity |
| Kevin Bennett | ASU | Water diffusion as an MRI biomarker of cellular invasion in brain tumors |
| Kevin Bennett | ASU | Aquaporins as MRI reporter genes |
| Nikolay Martirosyan | BNI | Manganese enhanced MRI for detection of spinal cord injury |
| Vinodh Naraynan | BNI | Axonal transport in the NF1-/+ mouse in vivo: an MEMRI study |
| Mark Preul | BNI | Anatomico-Histopathological validation of Right and Left Insular cortices using 7T-MR DTI on ex-vivo cadaver brains |
| Mark Preul | BNI | Comparison of 7T diffusion imaging with fiber histology in an ex-vivo sheep brain |
| Jiong Shi | BNI | Imaging CNS inflammation and autoimmune pathology in murine models of multiple sclerosis |
| Fu-Dong Shi | BNI | NK Cells and Myelin-Reactive Th17 Cells |
| Leland Hu | Mayo Clinic | Perfusion MRI to identify Bevacizumab failure in murine xenograft glioma models |
| Jason Kaufman | Midwestern University | Correlating MRI, histology, and functional recovery in a lateral compression model of rodent spinal cord injury |
| Clifford Whatcott | TGen | Measuring pH in Tumor Through MRI Technology |